A noninvasive ultrasonic method for vascular input impedance determination applied in diagnosis of the carotid arteries

In this study, a new method is presented for diagnosis of the extracranial carotid
arteries, based on analysis of the vascular input impedance noninvasively determined in
human common carotid arteries. The input impedance calculations were based on
simultaneous measurements of the blood pressure and the blood flow using the ultrasonic
Doppler and echo methods. In the analysis of the vascular input impedance a four-element
model was applied, whose elements represented the vessel resistance (Ro), the peripheral
resistance (RII
), the vessel compliance (C) and the inertance (L). The values of these elements
were determined by computer simulation of the vascular input impedance using the input
impedance of the model. The index of the optimum impedance simulation was the degree of
agreement between the blood flow measured in the common carotid artery and the blood
flow calculated from the input impedance of the model and the blood pressure. Preliminary
clinical investigations were performed in 43 healthy persons and 9 sick patients. The
obtained results indicate that the ratio between the vessel resistance (Rol and the peripheral
resistance (R,J as determined by the proposed measurement method and analysis of. the
vascular input impedance can be an indicator in identification of stenosis and occlusions of
the extracranial carotid arteries. The method described in the study permits identification of
stenosis of the internal carotid arteries of ~ 30%. The degree of the patency of the carotid
arteries in sick persons was determined from X-ray arteriographic examinations. which were
confirmed by surgical operations in 8 cases.